Muscatine County Iowa (Historic Districts) has 11 places on the National Register of Historic Places including 1 place of National significance and 1 place of Statewide significance. Significant places include Lock and Dam No. 16 Historic District and Fairport Biological Station Historic District, Downtown Commercial Historic District, Fair Oaks Historic District and Ijem Avenue Commercial Historic District.
Some of the country's most noteable architects helped create the Muscatine County places including U.S. Army Corps of Engineers, Willet L. Carroll, Paul V. Hyland, Cleveland and Jay and Joseph E. Mills. Prominent architectural styles found in Muscatine Country are Classical Revival, Italianate and Federal.