Lee County Iowa (Historic Districts) has 9 places on the National Register of Historic Places including 1 place of National significance and 1 place of Statewide significance. Significant places include Lock and Dam No. 19 Historic District and Iowa State Penitentiary Cellhouses Historic District, Atchison, Topeka and Santa Fe Passenger and Freight Complex Historic District, Faeth Farmstead and Orchard District and Fort Madison Downtown Commercial Historic District.
Some of the country's most noteable architects helped create the Lee County places including Hugh L. Cooper, Montgomery Meigs, Henry Jackson Liebbe, Henry Franz Liebbe, O.C. Simonds, J.M. Dunham, C.F. Morse and Barry Byrne. Prominent architectural styles found in Lee Country are Late Victorian, Federal and Greek Revival.