Wheeler County Texas has 3 places on the National Register of Historic Places including 2 places of Statewide significance. Significant places include Battle of Sweetwater Creek and Route 66 Bridge over the Chicago, Rock Island and Gulf Railroad, Tower Station.
Some of the country's most noteable architects helped create the Wheeler County places including M.L. Grady and E.T. Parker. Prominent architectural styles found in Wheeler Country are Art Deco.