Prehistoric cultural affiliation(s) include Drew Phase/Late Woodland, Monongahela Indian and Fort Ancient dating back to 500.
Several famous people are associated with these Greene County historic places including Thomas Hughes, Corbly John and William Crawford.
Some of the country's most noteable architects helped create the Greene County places including T.B. Dinsmore, Lisbon Scott, William Lang, Lippencott Brothers, James Parreco, Stephen Acklin, Jack Hamilton, Ernest Thralls and J.W. Drumm. Prominent architectural styles found in Greene Country are Italianate, Greek Revival and Federal.