The famous person John Wesley Powell is associated with one of more of the Cape Girardeau County historic places.
Some of the country's most noteable architects helped create the Cape Girardeau County places including Henry Flad, Works Progress Administration, John Wesley Powell, George P. et al Bartling and Walter P. Manske. Prominent architectural styles found in Cape Girardeau Country are Mission/Spanish Revival, Early Commercial and Italianate.




